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FluHubWeek ending Sep 26, 2026

Testing at home

Home flu or COVID test: what your result means and what to do next

A home test can point you to the right treatment, but a negative result does not rule out flu. Here is what to do with each result.

If your test is positive for flu

  • Higher risk, pregnant, or getting worse: contact a clinician today. CDC recommends antiviral treatment as soon as possible for these groups.[5] Who is higher risk.[7]
  • Healthy adult within 2 days of symptoms: an antiviral is an option you can ask about.[5]
  • Healthy and past 2 days, improving: rest at home and watch for warning signs.
  • A child: call the child's pediatrician.

A home test does not come with a prescription. You still need a clinician, and you do not need a second test first: CDC says testing is not required to prescribe an antiviral.[4]

If your test is positive for COVID-19

COVID-19 has its own antiviral treatments, which need to start within 5 to 7 days of symptoms.[6] Contact a clinician, especially if you are older or have a higher-risk condition.

If your test is negative but you have symptoms

Do not take a negative result as the final word. Rapid antigen flu tests miss many cases: CDC lists sensitivity of about 53% to 54% for antigen tests read by eye.[3] FDA advises that anyone who tests negative and still has fever, cough, or shortness of breath may have flu, COVID-19, or another infection and should follow up.[1]

  • Higher risk: call a clinician anyway. Treatment decisions should not wait for a positive test.[5]
  • Checking for COVID-19: test again 48 hours later, for at least two tests.[2]
  • Everyone: stay home until you meet CDC's return rule, whatever the result.[8] How long flu is contagious.

Test types and their limits

TestWhat it tells youLimits
Home antigen, flu and COVID-19 combinationSeparate results for flu A, flu B, and COVID-19 in about 15 minutes. The first combination test authorized outside emergency use was cleared in 2024.[1]Lower sensitivity than molecular tests, so false negatives happen.[1]
Rapid antigen in a clinicFlu A and B, often read by a device.About 76% to 80% sensitive with a reader device.[3]
Molecular (PCR-type)Flu, and often COVID-19 and RSV.More accurate; usually done in a clinic, pharmacy, or lab.[4]

A home test result also helps you protect others: if you live with someone at high risk, a positive flu result is a reason to ask about preventive antivirals for them.

Common questions

I tested positive for flu at home. Do I need another test?

Usually not. CDC says testing is not required to prescribe an antiviral, and treatment should not be delayed for results.[4] Tell the clinician which test you used and when.

My home test is negative but I feel awful. Could it still be flu?

Yes. Rapid antigen tests miss many flu cases, so a negative result does not rule flu out.[3] FDA advises that people who test negative and still have symptoms may have flu, COVID-19, or another infection and should follow up with a clinician.[1]

Should I test again?

For COVID-19, FDA recommends testing again 48 hours after a negative antigen test if you have symptoms, for at least two tests.[2] For flu, if you are in a higher-risk group, call a clinician rather than waiting on a second test.[5]

Related

Sources

  1. FDA. FDA authorizes marketing of first home flu and COVID-19 combination test outside of emergency use authorities, October 7, 2024.
  2. FDA. Understanding At-Home OTC COVID-19 Antigen Diagnostic Test Results, content current as of June 11, 2024.
  3. CDC. Rapid Influenza Diagnostic Tests, updated June 22, 2026.
  4. CDC. Guide for considering influenza testing when influenza viruses are circulating in the community, updated December 19, 2025.
  5. CDC. Influenza Antiviral Medications: Summary for Clinicians, updated March 10, 2026.
  6. CDC. Similarities and Differences between Flu and COVID-19, updated September 17, 2024.
  7. CDC. People at Increased Risk for Flu Complications, updated September 11, 2024.
  8. CDC. Preventing Spread of Respiratory Viruses When You're Sick, updated August 18, 2025.